Articles tagged with "MGUS"

Monoclonal gammopathy of uncertain significance (MGUS)

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Monoclonal gammopathy of undetermined significance (MGUS) happens when abnormal white blood cells make abnormal proteins called M proteins. M proteins don’t usually cause issues. Most people with MGUS don’t have symptoms. But a small percentage of people with this condition may develop blood cancer or a more serious blood disorder.

Raised light chains

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Serum free light chains are used to assess for clonally-restricted plasma cell populations. As such, they are only diagnostically useful and reflect possible pathological plasma cell conditions when there are elevated kappa or lambda serum free light chains AND the ratio of kappa to lambda free light chains is abnormal.